Vladimir Denisov

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Principal Investigator
Vladimir Denisov is a researcher in Biomedical Engineering at Lund University.

Project in third call:

Altered metabolism in type 2 diabetes and its complications – metabolite profiling and metabolic imaging using correlative NMR, MS and HP-MR techniques

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Principal Investigator
Vladimir Denisov is a researcher in Biomedical Engineering at Lund University.

Project in third call:

Altered metabolism in type 2 diabetes and its complications – metabolite profiling and metabolic imaging using correlative NMR, MS and HP-MR techniques

Principal Investigator
Vladimir Denisov is a researcher in Biomedical Engineering at Lund University.

Project in third call:

Altered metabolism in type 2 diabetes and its complications – metabolite profiling and metabolic imaging using correlative NMR, MS and HP-MR techniques

Short Biography

Vladimir Denisov is a researcher in Biomedical Engineering at Lund University.

AMBER postdoctoral fellowship subject (Third call)

Amyloid cardiomyopathy – the structural basis of transthyretin amyloidosis

When type 2 diabetes is diagnosed, a patient’s absolute risk of future disease complications remains very high despite available preventive therapies. It is thus imperative to determine key molecular mechanisms of the disease and their dependance on lifestyle and the environment. Our research teams focus on metabolic signatures of cardiovascular complications and dementia, as well as on development of experimental methods to identify new biomarkers and targets for drug discovery. 

This postdoctoral position seeks to bridge expertise in metabolomics, utilizing the available state-of-the-art nuclear magnetic resonance (NMR) and mass spectrometry (MS) techniques, and expanding into cutting-edge hyperpolarized-NMR (HPMR) metabolic imaging. This correlative approach, combined with data obtained through other -omics modalities aims to identify and develop novel molecular and metabolic biomarkers in the context of diabetes, obesity and related comorbidities. 

The position will be part the effort to close the gap between clinical and fundamental science in the area of metabolomics and molecular biomarkers of metabolic diseases. It will provide possibility for using the state-of-the-art experimental platforms and methods (NMR, MS) as well as for further development  of the novel technique (HPMR). This interdisciplinary effort involves a wide translational network of both biomedical and method-oriented researchers.

Location: Lund, Sweden

Organisation: Lund University

Links

AMBER call in EURAXESS main call (starting point for application)

Guide for applicants

Vladimir Denisov's profile in Lund University Research portal

Info about employment at Lund University