Hanna Isaksson
Principal Investigator
Professor Hanna Isaksson leads a group at the Department of Biomedical Engineering at Lund University. Her research area is primarily musculoskeletal tissue biomechanics and mechanobiology.
Project in second call:
High resolution imaging of the bone-cartilage interface in the knee during osteoarthritis
Principal Investigator
Professor Hanna Isaksson leads a group at the Department of Biomedical Engineering at Lund University. Her research area is primarily musculoskeletal tissue biomechanics and mechanobiology.
Project in second call:
High resolution imaging of the bone-cartilage interface in the knee during osteoarthritis
Principal Investigator
Professor Hanna Isaksson leads a group at the Department of Biomedical Engineering at Lund University. Her research area is primarily musculoskeletal tissue biomechanics and mechanobiology.
Project in second call:
High resolution imaging of the bone-cartilage interface in the knee during osteoarthritis
Short Biography
Prof. Hanna Isaksson joined the Division of Solid Mechanics at Lund University in 2011. Since 2014, she and her group moved to join the newly formed Department of Biomedical Engineering at Lund University. Her research area is primarily musculoskeletal tissue biomechanics and mechanobiology. In the hard tissue area, the research focuses on functional imaging and statistical shape modeling of bone, characterization of bone damage and fracture mechanisms as well as on improvement of bone quality during fracture repair. The team also works extensively on research questions related to structure-function-composition relationships of knee tissues and osteoarthritis, as well as understanding Achilles tendon biomechanics and mechanobiology following tendinopathy and tendon rupture.
Prior to joining Lund University, Dr Isaksson spend three years as a post-doctoral researcher at the Biophysics of Bone and Cartilage research group, University of Eastern Finland, working on experimental methods to determine bone quality in metabolic bone diseases, primarily osteoporosis. She obtained her PhD in Biomedical Engineering from Eindhoven University of Technology, the Netherlands, in a collaborative project between TU/Eindhoven and the AO Research institute in Davos, Switzerland. The project focused on mechanobiological modeling of bone regeneration.
AMBER postdoctoral fellowship subject (second call)
High resolution imaging of the bone-cartilage interface in the knee during osteoarthritis
Soft knee joint tissues connect or transmit forces during movement in the body. There specialized mechanical functions are due to their tailored microstructures and composition, based on a collagen network, small amounts of proteoglycans, and an extensive amount of water. Osteoarthritis (OA) is a joint disease where the tissues degenerate, which affects their composition, microstructure and mechanical performance. The position is within a larger project that strives to understand the development of OA, in order to develop tools for better prediction of the onset and progression of osteoarthritis in the knee joint tissues.
The goal for the post-doc is to focus on the bone-cartilage interface, and to develop, perform and analyse data from high resolution synchrotron-based experiments to untangle the structure-, composition and functional relationships at the immediate interface. Research questions related to how cartilage mineralization and subchondral bone adaptation occurs during OA can be explored using synchrotron-based tomography, scattering and spectroscopic techniques in 2D and 3D, ranging from tissue down to nanoscale.
AMBER postdoctoral fellowship subject (first call)
Structure-function relationships of soft knee tissues during dynamic loading
Soft knee joint tissues connect or transmit forces during movement in the body. Their specialized mechanical functions are due to their tailored microstructures and composition, based on a collagen network, small amounts of proteoglycans, and an extensive amount of water. Osteoarthritis (OA) is a joint disease where the tissues degenerate, which affects their composition, microstructure and mechanical performance. The position is within a larger project that strives to understand the development of OA, in order to develop tools for better prediction of the onset and progression of osteoarthritis in the knee joint tissues.
The goal for the post-doc specifically is to develop, perform, and primarily analyse data from high resolution experimental imaging of soft tissues, acquired mainly using synchrotron phase contrast X-ray tomography, but also other imaging modalities. The goal includes characterizing meniscus and cartilage microstructure and its relation to loading, based on in situ loading experiments during imaging.
Location: Lund, Sweden
Organisation: Lund University, Faculty of Engineering, Department of Biomedical Engineering
Links
AMBER call in EURAXESS main call (starting point for application)
Hanna Isaksson's profile in Lund University Research portal
Department of Biomedical Engineering's profile in Lund University Research portal