Felix Roosen-Runge
Principal Investigator
Felix Roosen-Runge is an Associate Professor in the Division of Physical Chemistry at Lund University, Sweden. His research addresses dynamics, structure and assembly in soft and biological matter by combining X-ray, light and neutron scattering methods with coarse-grained modeling and data science.
Project in second call:
Microscopic structure in plant seeds by scanning X-ray diffraction
Principal Investigator
Felix Roosen-Runge is an Associate Professor in the Division of Physical Chemistry at Lund University, Sweden. His research addresses dynamics, structure and assembly in soft and biological matter by combining X-ray, light and neutron scattering methods with coarse-grained modeling and data science.
Project in second call:
Microscopic structure in plant seeds by scanning X-ray diffraction
Principal Investigator
Felix Roosen-Runge is an Associate Professor in the Division of Physical Chemistry at Lund University, Sweden. His research addresses dynamics, structure and assembly in soft and biological matter by combining X-ray, light and neutron scattering methods with coarse-grained modeling and data science.
Project in second call:
Microscopic structure in plant seeds by scanning X-ray diffraction
Short Biography
Felix Roosen-Runge is an Associate Professor in the Division of Physical Chemistry at Lund University, Sweden. His research addresses dynamics, structure and assembly in soft and biological matter by combining X-ray, light and neutron scattering methods with coarse-grained modeling and data science. The most recent research activities are centered around proteins from sustainable plant sources, with the aim to understand processes such as protein extraction and hydrogel formation better from a physicochemical and soft matter perspective.
AMBER postdoctoral fellowship subject (second call)
Microscopic structure in plant seeds by scanning X-ray diffraction
Biological materials such as plant seeds, bone, and skin present a variability of microscopic structures, which in turn determine the complex functionality for life and health. The spatial variability of microscopic structure is of high importance to better understand how mechanical loads and chemical environments affect the materials in structure and function.
In this context, small- and wide-angle X-ray diffraction with a microfocus beam is an emerging technique with strong future prospects that allows to study the spatial distribution of specific nanoscopic structural patterns. In addition, simultaneous X-ray fluorescence allows to monitor the related chemical compositions in the different spots.
As central goal, this project aims at the characterization of macromolecular microstructure in plant seeds, and related implications for optimization of extraction protocols for more sustainable food products. Proteins from plant seeds present promising opportunities to replace animal-derived food proteins with a more sustainable, healthy and affordable protein source. However, plant seeds have been selected for efficient and long-lasting storage of proteins, so that an efficient non-destructive extraction of proteins presents a considerable challenge. In this context, microscopic structure is an essential information for novel extraction pathways.
Besides the experimental campaigns at large scale facilities such as MAX IV and ESRF, the central and significant task of the project is the development of reliable and suitable data analysis frameworks for the resulting large and multi-modal data sets. The activities will be embedded into an ongoing larger project on food proteins from plant seeds, and we will also aim to collaborate with additional research groups on relevant sample systems and questions.
Location: Lund, Sweden
Organisation: Lund University, Faculty of Science, Department of Biochemistry and Structural Biology
Links
AMBER call in EURAXESS main call (starting point for application)
Felix Roosen-Runge's profile in Lund University Research portal
Physical Chemistry's profile in Lund University Research portal